FIGURE 3.

Plasma levels before and after multiple oral administrations of Lumeneto capsules (µM). Phytoene level increased significantly (p < 0.001); almost 4 times within the first week of treatment and by 3–4 weeks the plasma level of phytoene was 0.37–0.32 µM which is almost 5 times the baseline level. Phytofluene level in the plasma increased 55% (p < 0.05) within the first week of treatment and continued to increase significantly (p < 0.001) for the course of the study. After 4 weeks of use, there was about 2.5 times the baseline level. There was a marked increase in blood plasma level of zeta‐carotene after treatment; it reached over 5 times baseline after 4 weeks of treatment (p < 0.001). The baseline plasma level of lycopene was high (1.58 µM), and it did not change over the course of treatment