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. 2022 Jul 21;66(18):2200164. doi: 10.1002/mnfr.202200164

Figure 8.

Figure 8

Proposed model of the effect of Roseburia hominis on neuroinflammation. R. hominis, a potential probiotic, alleviated neuroinflammation by producing the metabolites propionate and butyrate. The underlying mechanism of its beneficial effects might be the result of HDAC inhibition of microglia by propionate and butyrate.