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. 2022 Sep 8;52(12):e13866. doi: 10.1111/eci.13866

TABLE 2.

Age‐ and sex‐specific percentile values for serum sex steroids and sex steroid‐binding globulin

(A) Total estradiol (pmol/L)
Men							Women
Age‐groups	N	5^th	25^th	50^th	75^th	95^th	Age‐groups	N	5^th	25^th	50^th	75^th	95^th
45–49 year	212	41.93	63.70	86.92	109.43	155.55	45–49 year	245	18.35	32.37	165.30	512.50	1719.00
50–54 year	391	46.90	71.62	90.78	115.80	154.95	50–54 year	456	18.35	18.35	40.75	129.98	800.20
55–59 year	471	45.09	74.06	94.47	115.70	160.10	55–59 year	582	18.35	18.35	18.49	43.60	85.84
60–64 year	300	54.02	80.51	99.78	125.73	161.30	60–64 year	387	18.35	18.35	27.80	45.30	79.32
65–69 year	49	64.69	83.17	104.40	129.30	165.16	65–69 year	51	18.35	18.35	32.59	50.32	110.60
70–74 year	39	64.79	95.28	123.20	131.90	155.29	70–74 year	41	18.35	24.28	38.43	51.62	138.20
75–79 year	23	51.11	75.21	114.40	125.45	161.81	75–79 year	29	18.35	18.96	34.40	44.02	68.68

(B) Total testosterone (nmol/L)
Men							Women
Age‐groups	N	5^th	25^th	50^th	75^th	95^th	Age‐groups	N	5^th	25^th	50^th	75^th	95^th
45–49 year	212	10.05	14.43	17.98	22.97	28.00	45–49 year	245	0.37	0.59	0.80	1.06	1.66
50–54 year	391	9.97	13.97	17.27	21.79	27.63	50–54 year	452	0.38	0.57	0.80	1.10	1.63
55–59 year	471	9.60	13.05	16.67	20.82	27.70	55–59 year	580	0.34	0.55	0.73	1.01	1.70
60–64 year	298	9.25	12.78	16.31	20.43	26.95	60–64 year	386	0.38	0.59	0.82	1.12	1.68
65–69 year	49	9.55	12.46	17.26	20.30	27.82	65–69 year	51	0.36	0.59	0.86	1.11	1.53
70–74 year	39	9.61	12.15	15.77	19.43	24.08	70–74 year	41	0.30	0.55	0.81	1.13	1.61
75–79 year	23	10.34	12.01	13.46	18.00	22.84	75–79 year	28	0.31	0.60	0.78	1.14	2.74

(C) cFAI
Men							Women
Age‐groups	N	5^th	25^th	50^th	75^th	95^th	Age‐groups	N	5^th	25^th	50^th	75^th	95^th
45–49 year	212	0.33	0.40	0.49	0.57	0.71	45–49 year	245	0.004	0.009	0.013	0.018	0.028
50–54 year	391	0.30	0.39	0.45	0.53	0.70	50–54 year	452	0.004	0.009	0.013	0.021	0.034
55–59 year	471	0.25	0.35	0.41	0.49	0.62	55–59 year	580	0.005	0.009	0.014	0.020	0.039
60–64 year	298	0.26	0.33	0.40	0.47	0.60	60–64 year	386	0.006	0.011	0.016	0.023	0.037
65–69 year	49	0.23	0.29	0.35	0.43	0.55	65–69 year	51	0.006	0.011	0.014	0.022	0.032
70–74 year	39	0.19	0.25	0.31	0.40	0.52	70–74 year	41	0.005	0.009	0.017	0.021	0.038
75–79 year	23	0.24	0.27	0.28	0.34	0.37	75–79 year	28	0.005	0.007	0.012	0.018	0.035

(D) SHBG (nmol/L)
Men							Women
Age‐groups	N	5^th	25^th	50^th	75^th	95^th	Age‐groups	N	5^th	25^th	50^th	75^th	95^th
45–49 year	212	18.92	28.57	37.85	47.68	66.01	45–49 year	245	26.18	45.27	67.08	92.76	171.94
50–54 year	391	19.21	29.53	38.61	50.11	65.40	50–54 year	456	25.38	42.26	59.41	82.89	128.95
55–59 year	471	21.61	31.68	41.12	50.75	70.68	55–59 year	582	24.70	39.53	54.89	76.49	115.51
60–64 year	300	20.40	31.76	41.73	52.78	76.27	60–64 year	387	25.79	39.61	52.31	71.97	109.15
65–69 year	49	25.36	35.48	43.48	58.55	90.36	65–69 year	51	32.66	41.40	53.65	69.00	96.64
70–74 year	39	24.00	38.45	47.32	63.30	91.73	70–74 year	41	27.57	38.93	49.29	75.93	110.80
75–79 year	23	32.03	40.48	49.14	64.64	89.16	75–79 year	29	34.23	52.26	74.90	86.62	132.14

(E) DHEA (nmol/L)
Men							Women
Age‐groups	N	5^th	25^th	50^th	75^th	95^th	Age‐groups	N	5^th	25^th	50^th	75^th	95^th
45–49 year	209	6.85	12.67	17.77	25.32	46.77	45–49 year	241	5.12	10.14	14.71	23.24	45.23
50–54 year	389	6.10	9.45	14.42	20.84	38.67	50–54 year	450	4.83	10.17	14.94	22.03	38.70
55–59 year	459	5.07	8.51	12.69	18.19	30.93	55–59 year	573	4.54	8.67	13.24	19.18	32.92
60–64 year	294	4.25	7.23	10.15	16.40	27.64	60–64 year	384	4.28	8.52	12.92	19.34	34.77
65–69 year	49	3.75	6.28	9.12	12.62	23.47	65–69 year	51	3.08	7.34	9.19	13.22	23.78
70–74 year	39	2.74	3.91	6.42	10.05	19.62	70–74 year	41	2.63	4.13	7.28	11.98	22.34
75–79 year	23	2.47	3.39	4.61	9.72	14.45	75–79 year	27	2.20	3.15	5.60	8.88	16.88

Men							Women
Age‐groups	N	5^th	25^th	50^th	75^th	95^th	Age‐groups	N	5^th	25^th	50^th	75^th	95^th
45–49 year	193	2027.79	3487.16	4835.29	6171.53	7458.33	45–49 year	242	786.85	1878.14	3067.44	4197.49	6546.83
50–54 year	360	1613.14	2839.77	4055.80	5367.02	7030.06	50–54 year	447	866.30	1662.73	2545.95	3771.91	5684.64
55–59 year	455	1175.83	2472.76	3612.80	5043.47	6815.23	55–59 year	577	660.39	1408.54	2323.50	3317.62	5200.07
60–64 year	286	946.81	1872.69	2913.95	4264.78	7004.31	60–64 year	386	649.74	1313.61	2016.49	2923.86	5072.82
65–69 year	49	788.18	1470.75	2393.82	3464.91	5564.23	65–69 year	51	522.88	1034.04	1592.58	2745.01	4593.76
70–74 year	39	668.93	1057.61	1508.26	2525.77	4943.30	70–74 year	41	251.97	862.73	1494.59	2077.82	3038.15
75–79 year	23	558.24	970.90	1491.19	2573.66	4170.95	75–79 year	29	136.07	541.30	1065.05	1588.92	3108.19

(G) Androstenedione (nmol/L)
Men							Women
Age‐groups	N	5^th	25^th	50^th	75^th	95^th	Age‐groups	N	5^th	25^th	50^th	75^th	95^th
45–49 year	211	2.00	3.04	3.86	4.75	8.01	45–49 year	245	1.32	2.30	3.33	4.39	7.33
50–54 year	391	2.02	2.81	3.48	4.49	6.55	50–54 year	451	1.26	2.15	2.97	3.98	6.17
55–59 year	469	1.79	2.55	3.19	4.30	6.18	55–59 year	577	1.17	1.80	2.49	3.30	5.57
60–64 year	298	1.73	2.43	3.10	4.14	5.87	60–64 year	386	1.12	1.84	2.53	3.39	5.41
65–69 year	49	1.47	2.07	2.73	3.67	5.85	65–69 year	50	1.18	1.65	2.28	3.01	4.50
70–74 year	39	1.25	1.76	2.60	3.56	4.74	70–74 year	41	0.94	1.57	1.79	2.64	4.64
75–79 year	23	1.28	1.93	2.18	3.03	4.20	75–79 year	29	0.78	1.37	1.80	2.42	3.60

Abbreviations: N; number, cFAI; calculated free androgen index, SHBG; sex steroid‐binding globulin, DHEA; dehydroepiandrosterone, DHEAS; dehydroepiandrosterone sulfate.