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. 2022 Dec 14;14(12):873. doi: 10.3390/toxins14120873

Table 2.

Summary of the main CYP-enzymes involved in the human metabolism of the listed mycotoxins.

Mycotoxin Involved CYP-Enzymes References
AFB1 CYP3A4, CYP3A5, CYP3A7, CYP1A2, CYP2A13 [55,56,57,58]
DON No phase I metabolism [59,60,61,62,63]
T-2 CYP3A4, CYP2E1, CYP1A2, CYP2B6, CYP2D6 and CYP2C19 [64,65]
ZEN CYP3A4, CYP3A5, CYP2C8, CYP1A2 [66,67]
FB1 No phase I metabolism [68,69,70,71]
ENN B1 CYP3A4, CYP3A5, CYP1A2, CYP2C19 [72,73]