Table 2.

Effects of resveratrol analogs against cervical cancer: in vitro evidence.

Cell	Analog Name	Resveratrol Concentration/Duration	Effect	Reference
HeLa	8-ADEQ	8 µM 25 h	↓proliferation ↑Cell cycle arrest at G2/M phase ↑cyclin B1 levels ↑Cdk1, Cdc25C phosphorylation ↑Chk1, Chk2 activation ↑ATM/ATR activation	[64]
HeLa	Pterostilbene	0–400 µM 24–48 h	↑Cell morphology ↓Cell growth ↑DNA fragmentation ↓Proliferation ↑Apoptosis ↓p-mTOR ↓p-PI3K ↓p-Akt	[65]
HeLa	N-(4-methoxyphenyl)-3,5-dimethoxybenamide (MPDB)	35 µM 15 h	↓Cell growth ↓Survival ↑Cell cycle arrest at G2/M phase ↓Proliferation ↑DNA fragmentation ↑Apoptosis ↑Cdc2 ↑Cdc25c ↑Chk1/2 ↑p53 ↓Bcl-xL ↑Fas ↑Caspases-3/-8/-9 ↑Cleaved PARP	[66]
TC1	Pterostilbene	20, 30 µM 48 h	↓Cell viability ↑Cytotoxicity ↑Apoptosis ↓E6	[67]
HeLa	Pterostilbene	20 µM 24–48 h	↓Cell growth ↓Survival ↓Metastasis ↑Cell cycle arrest at S and G2/M phase ↑p21/53 protein levels ↓Cyclin E1/B1 ↓Bcl-2 protein levels ↓Bcl-xL protein levels ↑Cleaved caspases-3/-9 ↓MMPs-2/-9	[68]