Table 2.
Characteristics of reports of spontaneous statin reactions, included in the SOC “psychiatric disorders”, recorded in EudraVigilance (January 2004–July 2021).
| Atorvastatin n = 3659 N, (%) |
Simvastatin n = 2326 N, (%) |
Rosuvastatin n = 1962 N, (%) |
||
|---|---|---|---|---|
| Age category | 18–64 years | 1756 (47.99) | 1155 (49.66) | 943 (48.06) |
| 65–85 years | 1284 (35.09) | 810 (34.82) | 693 (35.32) | |
| Gender | Male | 1522 (41.60) | 1111 (47.76) | 805 (41.03) |
| Female | 2039 (55.73) | 1129 (48.54) | 1122 (57.19) | |
| Reporter group | Health professionals | 2172 (59.36) | 1732 (74.46) | 1126 (57.39) |
| Non-health professionals | 1422 (38.86) | 573 (24.63) | 835 (42.56) | |
| Seriousness | Serious ADRs | 2911 (79.56) | 1718 (73.86) | 1581 (80.58) |
| Non-serious ADRs | 740 (20.22) | 596 (25.62) | 380 (19.37) | |
| Countries | EEA | 2175 (59.44) | 1294 (55.63) | 602 (30.68) |
| Non-EEA | 1454 (39.74) | 1032 (44.37) | 1360 (69.32) | |