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. 2022 Nov 29;15(12):1489. doi: 10.3390/ph15121489

Table 6.

Kinetic models for NPs prepared using different PLGA grades. R2_adj.; adjusted coefficient of determination, AIC; Akaike information criterion, MSE; mean squared error, MSC; model selection criteria.

Parameter/Model PLGA (50:50) NPs PLGA (75:25) NPs Resomer RG 503H NPs
R2_adj AIC MSE MSC R2_adj AIC MSE MSC R2_adj AIC MSE MSC
Zero-order 0.76 97.31 27.95 1.28 0.71 94.12 22.6 1.03 0.8 103.3 42.85 1.4
First-order 0.83 91.44 20.03 1.65 0.77 90.2 17.77 1.28 0.87 97.22 28.13 1.78
Hixson-Crowell 0.81 93.49 22.47 3.49 0.75 91.54 19.28 1.2 0.85 99.26 32.5 1.65
Quadratic 0.95 73.39 6.32 2.78 0.92 70.41 6.08 2.52 0.94 86.72 12.87 2.44
Higuchi 0.97 65.3 3.8 3.28 0.97 58.33 2.41 3.27 0.96 79.27 9.03 2.9
Korsmeyer–Peppas 0.98 62 2.93 3.49 0.97 56.79 2.12 3.37 0.97 77.8 7.23 2.99
Weibull 0.99 35.22 0.59 5.16 0.99 42.84 0.79 4.24 0.98 54 3.96 4.48