TABLE 5.

Genotypes of patients with PD and healthy volunteers (control subjects), stratified by sex, according to different genetic models

Variant	Genotype, n (%)			Codominant OR (95% CI)	P, Pc	Dominant OR (95% CI)	P, Pc	Recessive OR (95% CI)	P, Pc	Overdominant OR (95% CI)	P, Pc
Women
rs1922452	AA	AG	GG
Control	79 (16.7)	225 (47.6)	169 (35.7)
PD	42 (12.6)	153 (45.8)	139 (41.6)	0.87 (0.63–1.20) 0.61 (0.37–1.00)	.140, .300	0.81 (0.59–1.10)	.170, .210	0.66 (0.42–1.04)	.071, .213	0.98 (0.73–1.33)	.910, .910
rs951818	AA	AC	CC
Control	168 (35.5)	229 (48.4)	76 (16.1)
PD	134 (40.1)	155 (46.4)	45 (13.5)	0.77 (0.55–1.07) 0.71 (0.45–1.13)	.200, .300	0.75 (0.55–1.03)	.076, .210	0.83 (0.54–1.27)	.380, .430	0.85 (0.63–1.15)	.280, .795
rs870849	CC	CT	TT
Control	185 (39.1)	221 (46.7)	67 (14.2)
PD	122 (36.5)	160 (47.9)	52 (15.6)	1.19 (0.85–1.66) 1.30 (0.83–2.04)	.430, .430	1.22 (0.89–1.67)	.210, .210	1.18 (0.79–1.78)	.430, .430	1.10 (0.81–1.49)	.530, .795
Men
rs1922452	AA	AG	GG
Control	61 (15.6)	189 (48.2)	142 (36.2)
PD	32 (10.8)	141 (47.8)	122 (41.4)	0.83 (0.61–1.12) 0.65 (0.42–1.00)	.120, .360	0.78 (0.58–1.04)	.090, .270	0.72 (0.48–1.07)	.100, .300	0.93 (0.70–1.23)	.620, .740
rs951818	AA	AC	CC
Control	131 (33.4)	197 (50.3)	64 (16.3)
PD	118 (40.0)	136 (46.1)	41 (13.9)	0.85 (0.63–1.15) 0.74 (0.48–1.14)	.340, .510	0.82 (0.62–1.10)	.180, .270	0.81 (0.55–1.21)	.310, .465	0.92 (0.70–1.22)	.570, .740
rs870849	CC	CT	TT
Control	155 (39.5)	178 (45.4)	59 (15.1)
PD	103 (34.9)	141 (47.8)	51 (17.3)	1.10 (0.81–1.49) 1.18 (0.77–1.81)	.720, .720	1.12 (0.84–1.49)	.460, .460	1.12 (0.75–1.66)	.580, .580	1.05 (0.79–1.39)	.740, .740

Abbreviation: PD, Parkinson's disease.