Table 3.

Enriched diseases with number of inferred gene‐diseases relationship identified using gene set analysis (from The Comparative Toxicogenomics Database http://ctdbase.org)

Disease name	Disease ID	p‐value	Corrected p‐value	Annotated genes number
Cardiovascular diseases	MESH:D002318	8.61E‐47	1.80E‐43	212
Heart diseases	MESH:D006331	1.61E‐39	3.37E‐36	165
Vascular diseases	MESH:D014652	7.01E‐25	1.46E‐21	124
Myocardial ischemia	MESH:D017202	1.64E‐16	3.43E‐13	64
Cerebrovascular disorders	MESH:D002561	5.72E‐11	1.19E‐07	37
Brain ischemia	MESH:D002545	5.49E‐10	1.15E‐06	24
Cardiovascular abnormalities	MESH:D018376	2.65E‐08	5.53E‐05	32
Heart defects, congenital	MESH:D006330	3.91E‐08	8.16E‐05	30
Arrhythmias, cardiac	MESH:D001145	8.79E‐08	1.83E‐04	33
Atrial fibrillation	MESH:D001281	3.76E‐07	7.85E‐04	25
Hypertension	MESH:D006973	4.70E‐07	9.80E‐04	28
Cardiomyopathies	MESH:D009202	2.51E‐06	0.00524	33
Heart failure	MESH:D006333	3.53E‐06	0.00738	22
Stroke	MESH:D020521	3.89E‐06	0.00813	17