Coaxial electrospinning. (A) CS, CS1, and CS2 fiber membrane in vitro drug release curve (full range and first 4 h) (reprinted with permission from [188]. Copyright©2016, Elsevier B.V. All rights reserved). (B) ROX drug release curve: (a) 14 days and (b) 10 h (reprinted with permission from [192]). (C) (a) Formation mechanism of engineering SOS, (b) overview of biphasic release of typical drugs, (c) percentage of drug release curve vs. time, (d) time required to release a certain amount of the loaded drug from an EHDA product (reprinted with permission from [194]. Copyright©2021, Donghua University, Shanghai, China).