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Plasma IgA (A), IgG (B), and IgG subclass (day 42) (C) antibody responses to SBR from mice immunized by the i.n. route with SBR alone, SBR-CTA2/B, or SBR–LT-IIaA2/B. Data represent the arithmetic means + standard deviations (error bars) of eight mice per group. ∗, statistically significant differences at P < 0.05 compared to SBR–LT-IIaA2/B.
