TABLE 2.
Significant differences in R2* among obstructive sleep apnea groups. Findings are s−1 and are presented as adjusted mean ± standard error. Data were analysed by analysis of covariance using R2* as the dependent variable and obstructive sleep apnea groups as independent variable. Models are adjusted for age, time between polysomnography and MRI, sex, body mass index, diabetes, dyslipidaemia, hypertension, smoking, and continuous positive airway pressure treatment
No OSA | Mild OSA | Moderate OSA | Severe OSA | p | |
---|---|---|---|---|---|
n = 241 (31.2%) | n = 286 (37.0%) | n = 164 (21.2%) | n = 82 (10.6%) | ||
L superior frontal gyrus | 17.91 ± 0.12 | 17.95 ± 0.12 | 17.94 ± 0.12 | 18.36 ± 0.13 a , b , c | 0.003 |
L orbital gyri | 17.44 ± 0.10 | 17.50 ± 0.10 | 17.43 ± 0.10 | 17.81 ± 0.11 a , b , c | 0.002 |
R middle temporal gyrus | 17.88 ± 0.12 | 18.02 ± 0.12 | 18.02 ± 0.12 | 18.35 ± 0.14 a , b , c | 0.004 |
L middle temporal gyrus | 21.22 ± 0.20 | 21.44 ± 0.19 | 21.54 ± 0.19 | 22.15 ± 0.22 a , b , c | <0.001 |
L angular gyrus | 19.60 ± 0.15 | 19.78 ± 0.15 | 19.77 ± 0.15 | 20.24 ± 0.17 a , b , c | 0.001 |
L supramarginal gyrus | 19.94 ± 0.14 | 20.09 ± 0.14 | 20.07 ± 0.14 | 20.50 ± 0.16 a , b , c | 0.003 |
R cuneus | 20.19 ± 0.14 | 20.36 ± 0.14 | 20.55 ± 0.14 a | 20.84 ± 0.16 a , b | <0.001 |
Note: Bold text indicates p <0.005.
Abbreviations: L, left; R, right.
Significant difference compared with no OSA group.
Significant difference compared with mild OSA group.
Significant difference compared with moderate OSA group.