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. 2022 Nov 29;58(12):1749. doi: 10.3390/medicina58121749

Figure 7.

Figure 7

Hyp reduced NLRP1 inflammasome activation and inflammatory response in the hippocampus of chronic-stress-induced mice. (A–C) Statistical results show that Hyp decreased the mRNA expression of (A) NLRP1, (B) ASC, and (C) caspase-1 in the hippocampus of chronic stress-induced mice. (D–G) Statistical results show that Hyp reduced the mRNA levels of (D) IL-6, (E) IL-18, (F) IL-1β, and (G) TNF-α in the hippocampus of chronic-stress-induced mice. Results are shown as the mean from multiple experiments, n = 5, one-way ANOVA, followed by Dunnett multiple comparison test; * p < 0.05, ** p < 0.01, and *** p < 0.001.