Table 1.
Baseline characteristics.
| Parameter | n = 215 |
|---|---|
| Age (years) | 64.2 ± 13.3 |
| Male | 160 (74.4) |
| BMI | 28.2 ± 11.9 |
| Logistic EuroSCORE II | 15.6 ± 10.9 |
| Coronary artery disease | 50 (23.2) |
| Peripheral occlusive disease | 28 (13.0) |
| Diabetes mellitus | 41 (19.1) |
| Malignancies | 31 (14.4) |
| Serum kreatinin (mg/dL) | 1.6 ± 2.2 |
| Chronic hemodialysis | 18 (8.4) |
| Immunosuppression | 15 (7.0) |
| i.v. drug abuse | 9 (4.2) |
| NYHA functional class III/IV | 104 (48.4) |
| Native valves | 160 (74.4) |
| IE affected valves | |
| Aortic valve only | 114 (52.3) |
| Mitral valve only | 80 (37.2) |
| Combined aortic and mitral | 21 (9.8) |
| Regurgitation degree II/III | |
| Aortic valve | 78 (57.7) |
| Mitral valve | 68 (67.3) |
| LVEF > 50% | 142 (66.0) |
| LVEF < 30% | 19 (8.8) |
| Embolism | 151 (70.2) |
| Cerebral | 77 (35.8) |
| Renal | 38 (17.7) |
| Spleen | 21 (9.8) |
| Eyes | 13 (6.0) |
| Other | 10 (4.6) |
| Fever | 185 (86.0) |
| WBC (1/nL) | 11.4 ± 5.5 |
| CRP (mg/L) | 90.1 ± 77.9 |
| PCT (ng/mL) | 4.3 ± 13.3 |
| Vegetation size (mm) | 14.8 ± 5.8 |
| NT-proBNP (pg/mL) | 4398 (1310, 11,830) |
| Log(NT-proBNP) | 3.62 ± 0.70 |
Values are n (%) or mean ± SD, except for NT-proBNP with median (IQR). BMI = body mass index; CRP = C-reactive protein; IE = infective endocarditis; LVEF = left ventricular ejection fraction; NT-proBNP = N-terminal prohormone of B-type natriuretic peptide; NYHA = New York Heart Association; PCT = procalcitonin; WBC = white blood cell count.