Table 5.
Clinical Model—Efficacy | |||||||
---|---|---|---|---|---|---|---|
N | Challenge Route | Challenge Dose | Challenge Strain | Challenge Timpoint (dpv) | Observation Period (dpc) | Readouts | Comments |
5 | IM | 103 HAD50 | Georgia | 28 | 21 | CS, T, V, TqPCR | proof-of concept [63] |
5 | |||||||
5 | |||||||
5 | 102 HAD50 | TTKN/ASFV/ DN/2019 |
28 | 15 | CS, T, V NS | efficacy in Yorkshire × Landrace crossbreed [64] | |
25 | CS, T | ||||||
5 | CS, T, V, NS | efficacy in Vietnamese Mong Cai crossbreed [64] | |||||
5 | |||||||
5 | |||||||
5 | |||||||
20 | CS, T | ||||||
18 | 14 | 14 | CS, T | efficacy in Yorkshire × Landrace and Vietnamese Mong Cai crossbreed [64] | |||
5 | 21 | ||||||
10 | 28 |
Readouts: CS = clinical signs, T = temperature, V = viremia, NS = nasal swab, TqPCR = tissue qPCR.