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Effect of compounds 4a, 4b, and 7d on caspases 3, 8, 9 and Cytochrome C.
| Comp. No | Caspase-3 | Caspase-8 | Caspase-9 | Cytochrome C | ||||
|---|---|---|---|---|---|---|---|---|
| Conc (pg/mL) | Fold Change | Conc (ng/mL) | Fold Change | Conc (ng/mL) | Fold Change | Conc (ng/mL) | Fold Change | |
| 4a | 587.50 ± 4.50 | 8.95 | 1.20 | 6 | 17.80 | 18.75 | 0.80 | 16 |
| 4b | 535.50 ± 4.50 | 8.15 | 0.80 | 4 | 16.60 | 17.50 | 0.70 | 14 |
| 7d | 485.50 ± 4.25 | 7.40 | -- | -- | -- | -- | -- | -- |
| Doxorubicin | 503.25 ± 4.50 | 7.70 | 1.80 | 9 | 16.25 | 17.00 | 0.60 | 12 |
| Control | 65.65 | 1 | 0.20 | 1 | 0.95 | 1 | 0.05 | 1 |
