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. 2022 Nov 24;14(12):2594. doi: 10.3390/pharmaceutics14122594

Scheme 2.

Scheme 2

Scheme 2

Illustration of hydrogen bonding formation of mPEG-CC-pONBMA (MCP) and glutathione (GSH) and proposed degradation of MCP upon UV light (A); proposed degradation route of mPEG-SS-pONBMA (MSP) upon UV light, GSH, and combined treatments (B); schematic illustration of the cellular uptake of DOX-loaded MSP nanoparticles (MSP-D) and DOX-induced necroptosis pathway with and without UV light irradiation (C).