Table 5.
Logistic regression analysis of GH and IGF1.
| Logistic Regression Analysis * | Standardized Beta Coefficients |
SE | p Value |
|---|---|---|---|
| GH, ng/mL | |||
| Total Cholesterol | 0.13 | 0.04 | 0.003 |
| HDL-Cholesterol | −0.17 | 0.06 | 0.008 |
| Triglycerides | −0.01 | 0.02 | 0.37 |
| Glucose | 1.7 | 0.02 | 0.002 |
| Insulin | 0.03 | 0.04 | 0.45 |
| HOMA-IR | −0.33 | 0.2 | 0.09 |
| Fibrosis | −2.3 | 0.31 | 0.001 |
| Portal Inflammation | 0.56 | 0.51 | 0.41 |
| Lobular Inflammation | −0.36 | 0.34 | 0.28 |
| TNF-a | −1.2 | 0.12 | 0.04 |
| IGF1, ng/mL | |||
| Total Cholesterol | 0.41 | 1.3 | 0.75 |
| HDL-Cholesterol | 0.68 | 1.97 | 0.72 |
| Triglycerides | −0.07 | 0.35 | 0.83 |
| Glucose | −0.69 | 0.71 | 0.32 |
| Insulin | 3.8 | 1.5 | 0.01 |
| HOMA-IR | −2.7 | 1.7 | 0.001 |
| Fibrosis | −2.8 | 1.1 | 0.001 |
| Portal Inflammation | −1.3 | 1.7 | 0.09 |
| Lobular Inflammation | −1.0 | 1.1 | 0.42 |
| TNF-a | −0.78 | 0.34 | 0.25 |
| IGFBP-3, µg/mL | |||
| Total Cholesterol | 0.01 | 0.01 | 0.46 |
| HDL-Cholesterol | −0.02 | 0.03 | 0.21 |
| Triglycerides | 0.01 | 0.04 | 0.69 |
| Glucose | −0.01 | 0.07 | 0.16 |
| Insulin | −0.02 | 0.016 | 0.94 |
| HOMA-IR | −0.09 | 0.07 | 0.20 |
| Fibrosis | −0.02 | 0.04 | 0.45 |
| Portal Inflammation | 0.41 | 0.54 | 0.35 |
| Lobular Inflammation | −0.01 | 0.9 | 0.74 |
| TNF-a | −0.11 | 0.02 | 0.85 |
* Adjusted for BMI, WC and gender. HDL = High Density Lipoprotein; HOMA-IR = HOmeostasis Model Assessment-estimated Insulin Resistance. The p values in bold are the significant ones.