Table 2.
Mortality hazard ratios (HR) and their confidence intervals (95% CI) according to the categories of the MADP score and for each two-point increment.
| Mediterranean Alcohol-Drinking Pattern | Only Among Drinkers | |||||
|---|---|---|---|---|---|---|
| Abstention | Low (0–3) | Moderate (4–5) | High (6–9) | Continuous (+2 Points in MADP) | p for Trend | |
| Cases/person-years | 35/3122 | 35/2207 | 102/10,113 | 119/13,316 | ||
| Age-adjusted | 0.46 (0.28–0.74) | 1 (ref.) | 0.61 (0.41–0.90) | 0.50 (0.34–0.74) | 0.84 (0.74–0.94) | 0.001 |
| p | 0.001 | 0.013 | 0.001 | 0.004 | ||
| Age- and sex-adjusted model | 0.53 (0.33–0.87) | 1 (ref.) | 0.63 (0.43–0.94) | 0.53 (0.36–0.78) | 0.87 (0.77–0.98) | 0.002 |
| p | 0.012 | 0.022 | 0.001 | 0.026 | ||
| Multivariable-adjusted model * | 0.60 (0.36–0.98) | 1 (ref.) | 0.65 (0.44–0.96) | 0.54 (0.37–0.80) | 0.90 (0.79–1.02) | 0.003 |
| p | 0.042 | 0.030 | 0.002 | 0.093 | ||
* Adjusted for sex, BMI (kg/m2), physical activity (MET-h/week), smoking habit (four groups and packages/year, four categories), punctuation in the Mediterranean Diet Score at baseline (three categories), number of metabolic conditions at baseline (hypercholesterolemia, hypertriglyceridemia, diabetes, obesity, and hypertension; three categories), and marital status (five categories).