Table 1.

Kinetic study of IBU permeation through artificial membranes from the examined commercial formulations and from the developed nanogels based on EPIβCD in combination with CRP or HPMC prepared by emulsion-solvent evaporation (E.M.) or by conventional (C.M.) methods.

Formulation	Zero-Order	First-Order	Higuchi	Korsmeyer–Peppas
	R2	R2	R2	R2	n
Lasonil	0.8138	0.8157	0.8988	0.9343	0.4
Vegetallumina	0.8517	0.8530	0.9869	0.9929	0.3
Dolofast	0.8708	0.8728	0.9413	0.9638	0.4
EPIβCD–CRP (E.M.)	0.9982	0.9985	0.9890	0.9985	0.6
EPIβCD–CRP (C.M.)	0.9936	0.9985	0.9890	0.9985	0.7
EPIβCD–HPMC (E.M.)	0.9933	0.9924	0.9771	0.9902	0.6