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IC50 measurement of the inhibition of S-protein RBD (BA.2.12.1) binding to heparin using solution competition SPR by sulfated glycans (heparin, PPS, and MPS). S-protein RBD concentration was 250 nM. Error bars represent standard deviations from triplicate tests. (A,B) = heparin; (C,D) = PPS; (E,F) = MPS.
