Figure 3.

Quantification of thiobarbituric acid reactive substances (TBARS) (nmol/g of protein) of dorsal wounds in adults male Wistar rats (Rattus norvegicus) on days 2, 7, or 12 after injury and daily local application of treatments based in the plant marcela (Achyrocline satureioides) extracts and controls. MPO (OD/mg of tissue): myelopeoxidase enzyme; TNF-α (pg/mg of protein): factor of tumor necrosis α; IL-1(pg/mg of protein): interleukin 1. NT: without treatment; HG: hydrogel; HNE: hydrogel containing blank nanoemulsion; and HNE_AS: hydrogel containing hydrogel incorporated in nanoemulsion. Analysis of variance followed by the Tukey test, a: there is statistical difference with NT (p < 0.05); b: there is statistical difference with HG (p < 0,05) and c: there is statistical difference with HNE (p < 0.05); n = 6.