Table 1.

Characterization of formulations applied in evaluations of wound healing from adults male Wistar rats (Rattus norvegicus) showed in the present study.

	Droplet Size (nm)	PI	ζ-Potential (mV)	Flavonoids Content (µg/mL)
HNEAS	250 ± 3.9	0.19 ± 0.09	−48.0 ± 2.6 a	1086.6 ± 1.9
HNE	210 ± 2.1	0.17 ± 0.01	−27.7 ± 4.0	-

HNE_AS: hydrogel containing Achyrocline satureioides extract incorporated in nanoemulsions; HNE: hydrogel containing blank nanoemulsion. The hydrogels were obtained by adding 0.15% of Carbopol^® Ultrez 20 directly to the nonemulsion. PI: Polydispersity index. Deviations are expressed as relative standard deviation (%). Analysis of variance followed by the Tukey test, ^a statistical difference with HNE (p < 0.05), n = 3.