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. 2022 Dec 6;14(12):2726. doi: 10.3390/pharmaceutics14122726

Table 4.

Evolution of dorsal wounds temperature of adults male Wistar rats (Rattus norvegicus) on days 0, 1, 2, 7, or 12 after injury and daily local application of treatments based in marcela (Achyrocline satureioides) extracts and controls.

Day 0 Day 1 Day 2 Day 7 Day 12
NT 32.8 ± 3.89 35.2 ± 5.11 34.0 ± 5.55 35.7 ± 4.52 a 35.6 ± 5.42 a
HG 33.4 ± 2.20 34.8 ± 4.80 33.1 ± 9.17 36.4 ± 2.95 a,b 35.2 ± 5.29
HNE 33.7 ± 2.40 33.9 ± 7.07 34.7 ± 2.86 34.0 ± 4.22 34.7 ± 4.83
HNEAS 33.7 ± 2.31 35.2 ± 2.14 34.1 ± 4.83 35.1 ± 3.52 35.7 ± 3.13 a

HG: animals treated with blank hydrogel; HNE: animals treated with blank nanoemulsion incorporated in hydrogel and HNEAS: animals treated with AS extract incorporated in nanoemulsions; NT: No treatment. Deviations are expressed as relative standard deviation (%). Analysis of variance followed by the Tukey test, a statistical difference with Day 0 (p < 0.05), b statistical difference with Day 2 (p < 0.05), n = 12.