Table 4.
Day 0 | Day 1 | Day 2 | Day 7 | Day 12 | |
---|---|---|---|---|---|
NT | 32.8 ± 3.89 | 35.2 ± 5.11 | 34.0 ± 5.55 | 35.7 ± 4.52 a | 35.6 ± 5.42 a |
HG | 33.4 ± 2.20 | 34.8 ± 4.80 | 33.1 ± 9.17 | 36.4 ± 2.95 a,b | 35.2 ± 5.29 |
HNE | 33.7 ± 2.40 | 33.9 ± 7.07 | 34.7 ± 2.86 | 34.0 ± 4.22 | 34.7 ± 4.83 |
HNEAS | 33.7 ± 2.31 | 35.2 ± 2.14 | 34.1 ± 4.83 | 35.1 ± 3.52 | 35.7 ± 3.13 a |
HG: animals treated with blank hydrogel; HNE: animals treated with blank nanoemulsion incorporated in hydrogel and HNEAS: animals treated with AS extract incorporated in nanoemulsions; NT: No treatment. Deviations are expressed as relative standard deviation (%). Analysis of variance followed by the Tukey test, a statistical difference with Day 0 (p < 0.05), b statistical difference with Day 2 (p < 0.05), n = 12.