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. 2022 Nov 22;12(12):1157. doi: 10.3390/metabo12121157

Figure 4.

Figure 4

Systems-level analysis of RNA-seq data and predicted metabolic fluxes. Principal component analysis (PCA) plots are shown for (A) all 23,873 genes, (B) 20,315 non-metabolic genes, (C) 3558 metabolic genes, and (D) 886 metabolic fluxes. The percent variability for PC1 and PC2 are shown. Minimum spanning trees (MST) are shown for (E) all genes, (F) non-metabolic genes, (G) metabolic genes, and (H) metabolic fluxes. In all MST plots, progressing AH disease severity is shown.