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. 2022 Dec 8;20(12):770. doi: 10.3390/md20120770

Table 3.

The residues of interactions between MMP-1 and ligands.

FH GSH
Hydrophobic interaction Leu181, Tyr240 Leu181, Tyr240
Hydrogen bonds Asn180, Leu181, Ala182, VAL215, Glu219, Tyr240 Asn180, Glu219, His228, Leu235, Thr241
Salt bridges - His228
π-stacking - -

Note: No interaction with the key amino acid residue.