Table 1.

Table summarizing the key interactions observed in the C-Kit/Ligands and c-Myc/Ligands complexes as obtained by molecular modeling. The table shows the nucleotides involved in the interactions together with the type of interactions (HB = Hydrogen Bond).

Ligands	C-Kit 3′-End Tetrad						c-Myc 3′-End Tetrad
	G4	C5	G8	C9	G16	G20	G21	G9	T10	G13	G18	A24	A25
aloe emodin (1)	π-π	π-π	π-π	HB		HB				π-π	π-π	HB
aloe emodin-8-glucoside (2)	HB, π-π	HB	π-π		HB	HB	HB	π-π	HB	π-π	HB	π-π	HB