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. 2022 Dec 20;12(1):2149352. doi: 10.1080/22221751.2022.2149352

Figure 3.

Figure 3.

Histological examination results. In the group of health control and DMA2017 treated, no histological change was observed in the heart, brain and limb muscle. (d) In the MEM-treated group of mice, myocardial cell necrosis occurred in the heart. (e) MEM-treated mice exhibited severe muscle fiber necrosis in the limb muscle (arrow). (f) In the brain of mice, eosinophilic neuronal necrosis was observed occasionally. All the pathological changes are indicated by arrow. Representative images are shown at a magnification of 200×. Scale bar: 200 μm.