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. 2022 Dec 23;8(51):eadc9245. doi: 10.1126/sciadv.adc9245

Fig. 5. Regulation of heme and NHI in Dox cardiac toxicity.

Fig. 5.

(A to D) Heme levels in whole blood (n = 7 to 11 per group) (A), plasma (n = 5 to 10 per group) (B), liver (n = 7 to 10 per group) (C), and heart (n = 8 to 9 per group) (D) as measured within 24 hours after completion of the 2-week Dox regimen in mice. (E and F) NHI in the liver (n = 7 to 10 per group) (E) and heart (n = 7 to 10 per group) (F) within 24 hours after completion of the 2-week Dox regimen in mice. Data were expressed as means ± SEM. Ordinary one-way ANOVA followed by the Tukey-Kramer test was used to compare the means of experimental groups.