Fig. 6.
Docking poses of compounds 89–07 (cyan) and 89–38 (pink) within the active site of PLpro (PDB ID 7LBR) and hydrophobicity surface of PLpro substrate binding site (magnified view) with 89–07, 89–38 and GRL0617 (in orange) (A) Ribbon view depicted on the left; magnified hydrophobicity surface on the right (colors: blue = greatest polarity; red = greatest hydrophobicity; white = intermediate). (B) 2D interactions of 89–07. (C) 2D interactions of 89–38.