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IL-33 deficiency impairs IL-6 and IL-23 production by BMDCs. BMDCs were induced and stimulated with LPS, and the concentrations of IL-6 (a) and IL-23 (b) in the culture supernatant were measured by ELISA. The data are expressed as the means ± SDs. Significant differences are shown by ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 by unpaired Student's t-tests comparing the WT and IL-33-KO groups. N = 3 for each group, and three independent repeated experiments were carried out.
