Table 1.

The list of enzymes involved in DNA methylation affected by the redox status of the cell.

Epigenetic process and modifying enzyme	Redox status influence on enzymes	Described roles for the epigenetic process	References
Methionine sulfoxide reductase (MSR)	NADP increases the MSR transcript, and GSH helps regenerate MSR	MSR regenerates methionine from the oxidized methionine pool	[52], [55]
Homologous gene silencing 1 (HOG1)	Nitrosylation of HOG1	Converts S-Adenosyl homocysteine to homocysteine	[50]
Detrahydrofolate reductase	NADPH is converted to NADP	Catalyzes the conversion of dihydrofolate to tetrahydrofolate	[48]
Methionine synthase (MS)	Nitrosylation	Converts homocysteine to methionine	[51]

Note: NADP, nicotinamide adenine dinucleotide phosphate; GSH, glutathione.