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. 2022 Dec 23;11(12):e202200252. doi: 10.1002/open.202200252

Table 2.

Influence of additives on selectivity.[a]

graphic file with name OPEN-11-e202200252-g003.jpg

Entry

Solvent

Base/additive

3 a [%][b]

4 a [%][b]

Selectivity 3 a/4 a

1

DMAc

K3PO4

27

31

0.87

2

DMAc

K3PO4/TBACl

9

46

0.19

3

DMAc

K3PO4/TBAF⋅H2O

42

4

DMAc

K3PO4/TBABr

12

45

0.27

5

DMAc

K3PO4/TBAI

4

13

0.31

6

DMAc

K3PO4/TBA[HSO4]

3

38

0.08

7

DMAc[c]

NaOMe

73

27

2.70

8

DMAc[c]

NaOMe/TBACl

7

93

0.08

9

DMAc[c]

NaOMe/NaCl[d]

28

13

2.15

10

DMAc[c]

NaOMe/KCl[d]

38

12

2.92

11

DMAc[c]

NaOMe/NH4Cl

30

34

0.88

[a] 1 equiv.=0.5 mmol, Atmospheric conditions unless otherwise noted. [b] Isolated yield. [c] Argon atmosphere. [d] 0.125 m solution in DMAc.