Table III.
Perioperative mortality and in-hospital complications following the use of an infraceliac versus a supraceliac proximal landing zone in fenestrated endovascular aneurysm repair of juxta-/pararenal abdominal aortic aneurysms
| Supraceliac Sealing zone (N=240) | Infraceliac Sealing zone (N=1246) | Supraceliac Sealing vs. Infraceliac Sealing Risk-adjusted Outcomes |
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|---|---|---|---|---|---|
|
| |||||
| Adjusted Kaplan-Meier Estimates | Hazards ratio | 95%-Confidence interval | p-value | ||
| Perioperative Mortality | 2.3% | 2.5% | 0.67 | 0.26-1.77 | .42 |
| 3-year Mortality | 11% | 12% | 0.89 | 0.53-1.50 | .67 |
| Completion Endoleaks | Unadjusted event rates | Unadjusted Odds Ratio | 95%- Confidence Interval | p-value | |
|
| |||||
| Type IA-Endoleak | 4.5% | 1.2% | .028 | ||
| Type IB-Endoleak | 1.6% | 0.5% | .30 | ||
| Type III Endoleak | 6.0% | 7.2% | .62 | ||
| Type II-Endoleak | 21% | 14% | .009 | ||
| Type IV-Endoleak | 0.8% | 3.2% | .001 | ||
| Undetermined Endoleak | 4.2% | 5.9% | .38 | ||
|
| |||||
| Graft-related Reinterventions | 1.4% | 3.1% | .81 | ||
| In-hospital Complications | Adjusted event rates | Adjusted Odds Ratio | 95%-Confidence Interval | p-value | |
|
| |||||
| Any Complication | 12% | 6.9% | 1.6 | 1.01-2.49 | .041 |
| Pulmonary Complications | 3.5% | 2.7% | 1.27 | 0.57-2.59 | .54 |
| Cardiac Complication | 5.5% | 1.9% | 2.61 | 1.29-5.13 | .006 |
| Myocardial Infarction | 4.4% | 1.8% | 2.33 | 1.12-4.76 | .023 |
| New-onset CHF | 1.1% | 0.4% | 2.69 | 0.57-12.1 | .18 |
| Bowel Ischemia | 1.7% | 1.5% | 0.83 | 0.24-2.27 | .75 |
| Stroke | 0.3% | 0.8% | 0.47 | 0.02-2.65 | .48 |
| Leg Ischemia | 3.0% | 0.9% | 3.15 | 1.02-9.47 | .039 |
| AKI | 16% | 11% | 1.55 | 1.05-2.26 | .024 |
| Postoperative Dialysis | 1.7% | 0.9% | 1.09 | 0.23-3.70 | .90 |
| Spinal Cord Ischemia | 1.7% | 0.8% | 2.21 | 0.70-6.38 | .15 |
| Reintervention/Reoperation | 6.0% | 4.2% | 1.49 | 0.80-2.64 | .19 |
This model was corrected for Age, Gender, Race, Diameter, Hypertension, Diabetes, Myocardial Infarction, Congestive Heart Failure (NYHAI/II / NYHAIII/IV), Smoking Status, Chronic Obstructive Pulmonary Disease, Obesity, Renal Dysfunction, Anemia, Prior Medication use (Aspirin, P2Y12-inhibitor, Statin, ACE/ARB), Prior Aortic Surgery, Aneurysm Extent (Zone 8/9), Repair type, Distal Sealing Zone, Low Center volume, Low Physician volume
CHF = Congestive Heart Failure; AKI = Acute Kidney Injury