Table 7.
Known-groups comparisons
| 4FS | Item 1 Tiredness at rest |
Item 2 Tiredness during activities |
Item 3 Muscle weakness at rest |
Item 4 Muscle weakness during activities |
Item 5 Balance problems |
Item 6 Vision problems |
Item 7 Abdominal discomfort |
Item 8 Muscle pain |
Item 9 Numbness |
Item 10 Headache |
|
|---|---|---|---|---|---|---|---|---|---|---|---|
| PhGA scores: Fair/Poor versus Excellent/Very Good | |||||||||||
| Poor PhGA (n = 7–14)* | 11.2 | 2.8 | 2.9 | 2.6 | 3.0 | 2.7 | 2.1 | 2.0 | 2.4 | 2.0 | 1.6 |
| Good PhGA (n = 2–6)* | 8.0 | 2.0 | 2.1 | 1.8 | 2.1 | 1.8 | 2.0 | 1.8 | 2.1 | 1.4 | 1.8 |
| Difference† | 3.2 | 0.8 | 0.8 | 0.8 | 0.9 | 0.9 | 0.1 | 0.2 | 0.4 | 0.6 | -0.2 |
| PGA scores: Fair/Poor versus Excellent/Very Good | |||||||||||
| Poor PGA (n = 14–20)* | 11.4 | 2.8 | 3.0 | 2.59 | 3.0 | 2.7 | 2.3 | 2.0 | 2.5 | 1.9 | 1.7 |
| Good PGA (n = 1–5)* | 8.1 | 2.1 | 2.2 | 1.76 | 2.1 | 1.8 | 1.9 | 1.3 | 1.6 | 1.5 | 1.2 |
| Difference† | 3.2 | 0.7 | 0.8 | 0.83 | 0.9 | 0.8 | 0.4 | 0.7 | 0.9 | 0.4 | 0.5 |
| 6MWT: < 400 m versus ≥ 400 m | |||||||||||
| < 400 m 6MWT group (n = 12–17)* | 10.9 | 2.7 | 2.8 | 2.5 | 2.9 | 2.6 | 2.3 | 1.8 | 2.3 | 1.9 | 1.5 |
| ≥ 400 m 6MWT group (n = 12–17)* | 10.4 | 2.6 | 2.8 | 2.3 | 2.7 | 2.3 | 2.1 | 2.0 | 2.3 | 1.7 | 1.7 |
| Difference† | 0.5 | 0.0 | 0.1 | 0.2 | 0.2 | 0.3 | 0.2 | -0.1 | 0.0 | 0.3 | -0.1 |
4FS = Fatigue 4 Scale; 6MWT = six-minute walk test; PGA = Patient Global Assessment; PhGA = Physician Global Assessment; SD = standard deviation
*Average
†Mean group difference averaged over time at examined visits