TABLE 1.

Adding recombinant mouse LBP to LBP^−/− plasma augments cytokine production by PEM stimulated with LPS^a

Conditions	Mean ± SDb for:
	TNF (pg/ml)c	IL-6 (pg/ml)c
Plasma-free medium	30 ± 15	20 ± 10
1% LBP−/− plasma	20 ± 5	30 ± 10
1% LBP−/− plasma + rmLBP	1,500 ± 120c	1,300 ± 250c
1% LBP−/− plasma + rmLBP + anti-LBP	40 ± 25	35 ± 25

^aPEM (50,000 cells/well) were stimulated for 6 h with 5 ng of LPS/ml in the presence of 1% LBP^−/− plasma, 1% LBP^−/− plasma plus 10 ng of rmLBP/ml, or 1% LBP^−/− plasma plus 10 ng of rmLBP/ml and 10 μg of neutralizing anti-LBP MAb (clone M330-19)/ml. 

^bData are from three different experiments run in duplicates. 

^cP < 0.05 by ANOVA.