Table 2.

Collection of individual data according to the children schedule at the AIRE research sites

	Inclusion All IMCI eligible consultation at PHC level	If hospitalized, recommended for all severe cases (respiratory and non-respiratory cases)		Follow-up visit: at the PHC, telephone call or home visit All severe cases regardless of hospitalization
	D-0	Entry	Discharge	Day-14 (+ 14 days)
Inclusion criteria Informed consent	✓
Socio-demographic characteristics, care pathway before attending PHC, IMCI classification	✓
Medical history and treatment	✓
Clinical examination (symptoms and signs) a	✓	✓	✓
Co-morbidities (malnutrition, anemia, malaria)	✓	✓
SpO2 Measurement by PO and integration into the IMCI classification (severe case if SpO2 < 90%)	✓	✓	✓
Use of Malaria Rapid Diagnostic Test (RDT)	✓	✓
Medical treatment (antibiotics, artemisinin -based combination treatment, salbutamol, etc.)	✓	✓	✓
Hospital referral decision for severe cases	✓
Missed opportunities of referral for severe cases and reasons				✓
Oxygen therapy		✓	✓
Laboratory evaluation, (full blood count, malaria RDT…) if applicable		✓
Evaluation of response to treatment		✓	✓
Treatment and management of comorbidities		✓	✓
Costs (households, and government perspective) b	✓	✓	✓	✓
Vital status			✓	✓

^a content of the clinical assessment changes depending on the place of examination

^b representative sub-sample of non-severe and severe cases