Table 2.
Quantitative EEG and volumetric MRI measures* by study groups
| qEEG/ERP Sample (n = 161) | |||||
| Dementia | MCI | SCD | Group comparisons | ||
| (n = 39) | (n = 53) | (n = 69) | F(2,156), p | Post-hoc tests | |
| P300b Amplitude | 10.6 (5.3) | 11.2 (4.9) | 14.2 (7.3) | 5.19, p = 0.007 | dementia<SCD, p < 0.003; |
| MCI < SCD, p < 0.03 | |||||
| Reaction Time | 618.2 (201.7) | 554.6 (97.4) | 529.8 (57.0) | 6.08, p = 0.003 | dementia>MCI, p < 0.05; |
| dementia > SCD, p < 0.0007 | |||||
| Commission Errors | 18.6 (19.8) | 6.6 (9.7) | 2.3 (2.6) | 31.71, p < 0.0001 | all p < 0.0001 |
| qEEG/ERP+vMRI Sample (n = 111) | |||||
| Dementia | MCI | SCD | Group comparisons | ||
| (n = 30) | (n = 39) | (n = 42) | F(2,106), p | Post-hoc tests | |
| P300b Amplitude | 10.3 (5.3) | 11.0 (4.8) | 13.8 (7.6) | 3.34, p = 0.04 | dementia<SCD, p < 0.02 |
| Reaction Time | 634.4 (217.3) | 535.9 (68.9) | 530.7 (55.1) | 6.88, p = 0.002 | dementia>MCI, p < 0.003; |
| dementia > SCD, p < 0.0006 | |||||
| Commission Errors | 16.5 (16.1) | 5.6 (7.8) | 2.5 (3.1) | 22.13, p < 0.0001 | dementia>MCI, SCD, p < 0.0001; |
| MCI > SCD, p < 0.04 | |||||
| Left Temporal Lobe Volume∧ | 78.5 (11.1) | 91.4 (16.7) | 99.1 (10.9) | 19.02, p < 0.0001 | dementia<SCD, p < 0.0001; |
| dementia < MCI, p < 0.009; | |||||
| MCI < SCD, p < 0.0004 | |||||
*Numbers indicate mean with standard deviation (SD). Note that while raw values are presented in the Table, log-transformed qEEG/ERP measures were used for all analyses. Group comparisons (ANOVAs) controlled for age and gender for qEEG/ERP measures and total intracranial volume additionally for vMRI measures. ∧F(2,105) for Left Temporal Lobe Volume, due to additional covariate.