Table 2.

Association of the Life’s Essential 8 scores with non-alcoholic fatty liver disease (NAFLD)

	Univariable model		Multivariable model 1*		Multivariable model 2†
	OR (95% CI)	p value	OR (95% CI)	p value	OR 95%CI	p value
LE8 score
Low (0–49)	1 (Reference)	/	1 (Reference)	/	1 (Reference)	/
Moderate (50–79)	0.38 (0.28–0.51)	< 0.01	0.55 (0.40–0.75)	< 0.01	0.53 (0.41–0.70)	< 0.01
High (80–100)	0.06 (0.04–0.11)	< 0.01	0.20 (0.11–0.34)	< 0.01	0.19 (0.12–0.30)	< 0.01
Per 10 points increase	0.53 (0.47–0.60)	< 0.01	0.68 (0.60–0.77)	< 0.01	0.67 (0.59–0.76)	< 0.01
Health behaviors score
Low (0–49)	1 (Reference)	/	1 (Reference)	/	1 (Reference)	/
Moderate (50–79)	0.98 (0.75–1.28)	0.58	0.90 (0.68–1.18)	0.43	0.95 (0.73–1.22)	0.93
High (80–100)	0.77 (0.55–1.09)	0.33	0.85 (0.59–1.22)	0.77	0.91 (0.61–1.34)	0.64
Per 10 points increase	0.93 (0.88–0.99)	0.02	0.95 (0.89–1.00)	0.05	0.97 (0.90–1.04)	0.23
Health factors score
Low (0–49)	1 (Reference)	/	1 (Reference)	/	1 (Reference)	/
Moderate (50–79)	0.25 (0.19–0.34)	< 0.01	0.36 (0.26–0.49)	< 0.01	0.34 (0.25–0.47)	< 0.01
High (80–100)	0.04 (0.02–0.05)	< 0.01	0.09 (0.06–0.14)	< 0.01	0.09 (0.05–0.14)	< 0.01
Per 10 points increase	0.53 (0.49–0.58)	< 0.01	0.61 (0.55–0.67)	< 0.01	0.60 (0.54–0.66)	< 0.01

OR odds ratio, CI confidence interval, LE8 life’s essential 8

^*Adjusted for age (as a continuous variable), sex, race/ethnicity, and obesity status

^†Additionally adjusted for poverty ratio (as a continuous variable), education levels, and marital status