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. 2022 Dec 20;9:1323–1339. doi: 10.2147/JHC.S392056

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© 2022 Huang et al.

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The effects of ARFIP2 on proliferation, invasion and migration are partially dependent upon the PI3K/Akt signalling pathway in HCC cells. (A) Levels of P62, AKT, p-AKT, Beclin 1, LC3B, and N-cadherin proteins were assessed in HepG2 and Huh7 cells stably-transfected with ARFIP2. (B) Effects of ARFIP2 on the PI3K/AKT signalling pathway after treatment with 20 µM LY294002 and 20 µM 740 Y-P.