Table 1.
Comparison of parameters between primary congenital glaucoma having normal visual field versus those with glaucomatous field loss
| Parameter | PCG eyes with normal VF | PCG eyes with VF loss | P |
|---|---|---|---|
| Age at examination (months) | 149.57±67 (60-348) | 194±97.2 (48-516) | 0.13 |
| Age at surgery (months) | 14.5±42 (0.4-228) | 39.3±94.4 (1-408) | 0.21 |
| Duration between surgery and examination (months) | 135±57.9 (54-324) | 154.7±66.6 (36-324) | 0.28 |
| Baseline IOP (mm Hg) | 24.6±5.9 (12-38) | 28.7±5.7 (16-40) | 0.03 |
| Baseline CDR | 0.54±0.2 (0.1-1) | 0.59±0.2 (0.1-0.9) | 0.319 |
| Baseline Corneal diameter (mm) | 13.2±1 (10.5-15) | 13.6±0.7 (12-15) | 0.317 |
| Maximum follow up IOP (mm Hg) | 18.2±5.8 (10-34) | 20.9±7.6 (12-44) | 0.15 |
| Minimum follow up IOP (mm Hg) | 6.64±2.9 (2-12) | 6.4±2 (2-10) | 0.33 |
| Mean follow up IOP (mm Hg) | 11.8±3.4 (6.38-18.9) | 12.4±3.4 (7.46-20.46) | 0.81 |
| Fluctuation IOP (mm Hg) | 3.2±1.5 (0.96-8.8) | 3.8±1.9 (1.38-9.83) | 0.16 |
| Final visual acuity (log MAR) | 0.25±0.3 (0.0-1.08) | 0.57±0.3 (0.0-1.08) | <0.001 |
| Final refraction (in Diopters) | −1.44±2 (−7.25 to+2.5) | −2.97±3 (−6.5 to+6.5) | 0.03 |
| RNFL average (µm) | 93.4±22 (45-146) | 78.5±33.6 (36-157) | <0.001 |
| TS RNFL (µm) | 123.5±30.4 (52-183) | 92.7±45 (30-165) | <0.001 |
| NS RNFL (µm) | 115.2±41.5 (0-186) | 86.2±49 (27-195) | 0.009 |
| NASAL (µm) | 72.3±22.6 (19-113) | 69.6±33.2 (25-156) | 0.73 |
| NI RNFL (µm) | 109±37.3 (10-119) | 81±38.5 (3-135) | 0.001 |
| TI RNFL (µm) | 121.7±27.4 (51-188) | 89±42.8 (15-146) | <0.001 |
| Temporal (µm) | 66.4±15.8 (36-119) | 58.7±11.2 (44-95) | 0.04 |
| Cup/disc ratio | 0.39±0.19 (0.06-0.76) | 0.49±0.3 (0.02-0.93) | 0.02 |
VF, Visual field; PCG, Primary congenital glaucoma; RNFL, Retinal nerve fiber layer; NI, Nasal inferior; TI, Temporal inferior; NS, Nasal superior; TS, Temporal superior. Significant P values shown in bold numbers