Figure 3.

Measurement of C5b-9 formation. Participants were divided by their vaccination status, type of vaccine, and dose of vaccine. Serum samples were incubated with RBD-coated plates; the formation of C5b-9 was subsequently measured using an indirect immunoassay. (S/N) represents the chemiluminescence signal generated from wells incubated with 1% serum divided by the signal in control wells incubated with PBST. (a) Represents formed C5b-9 levels while (b) and (c) represents a scatter plot that correlates C5b-9 to C1q and MBL levels, respectively, in BNT162b2 vaccinated individuals, Spearman's correlation coefficient (r_s), P value, and the number of participants (n) are displayed on the plot. (d) Individual values of C5b-9 per C1q in each participant were calculated and displayed in a scatter plot for the two types of vaccines. In scatter plots, each circle represents one participant, bold horizontal lines represent the mean of each group, while whiskers represent the standard deviation. Some error bars were clipped at the axis limit. Dunn's multiple comparisons statistical test following Kruskal–Wallis test was used to compare various groups to the unvaccinated group. Only significant pairwise comparisons are displayed, ^∗∗P ≤ 0.01, ^∗∗∗P ≤ 0.001.