Table 5.

Top 10 homologous GO templates in PDB generated by using I-TASSER server

Rank	1CscoreGO	2TM-score	3RMSDa	4IDENa	5Cov.	PDB Hit	Associated GO Terms
1	0.48	0.8621	1.11	0.36	0.88	1schA	GO:0042744, GO:0055114, GO:0004601, GO:0046872, GO:0005576, GO:0016491, GO:0006979, GO:0,020,037
2	0.47	0.8603	1.45	0.35	0.89	1fhfA	GO:0004601, GO:0006979, GO:0020037, GO:0055114
3	0.46	0.8466	1.35	0.37	0.87	1qgjA	GO:0005634, GO:0042744, GO:0016491, GO:0046872, GO:0005576, GO:0055114, GO:0005737, GO:0004601, GO:0006979, GO:0020037
4	0.46	0.8723	1.25	0.36	0.90	1pa2A	GO:0004601, GO:0005576, GO:0042744, GO:0055114, GO:0016491, GO:0046872, GO:0006979, GO:0020037
5	0.44	0.8680	1.40	0.34	0.90	1gx2A	GO:0004601, GO:0016491, GO:0042744, GO:0055114, GO:0046872, GO:0005773, GO:0005576, GO:0006979, GO:0020037
6	0.44	0.8946	0.38	0.36	0.90	3hdlA	GO:0004601, GO:0006979, GO:0020037, GO:0055114
7	0.44	0.8710	1.50	0.34	0.91	1bgpA	GO:0046872, GO:0055114, GO:0016491, GO:0004601, GO:0006979, GO:0020037
8	0.43	0.6619	2.08	0.25	0.71	1oafA	GO:0055114, GO:0005737, GO:0042744, GO:0016688, GO:0046872, GO:0004601 GO:0,016,491 GO:0,006,950 GO:0,006,979 GO:0,020,037
9	0.40	0.6526	2.70	0.22	0.72	1cyfA	GO:0004601, GO:0006979, GO:0020037, GO:0055114
10	0.40	0.6516	2.31	0.26	0.70	3riwB	GO:0004601, GO:0006979, GO:0020037, GO:0055114

1. Cscore^GO is a combined measure for evaluating the global and local similarity between query and template protein. Its range is [0–1], and higher values indicate more confident predictions. 2. TM-score measures global structural similarity between query and template protein. 3. RMSD^a is the RMSD between residues that are structurally aligned by TM-align. 4. IDEN^a is the percentage sequence identity in the structurally aligned region. 5. Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by the length of the query protein