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. 2022 Jan 1;13(1):25–34. doi: 10.32598/bcn.2021.144.4

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Copyright© 2022 Iranian Neuroscience Society

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Figure 1. — Centella asiatica (CA) improved Streptozotocin (STZ)-induced working memory deficits

Animals received ICV infusion of saline/STZ alone or combined with CA (150 and 300 mg/kg). CA significantly increased the alternative behavior at doses of 150 and 300 mg/kg (A). No significant difference was observed between the groups regarding the total arms entries (B).

^****P<0.0001 compared to the Control group. #P<0.01 and ##P<0.004 compared to the STZ -treated rats. Values are expressed as mean±SEM (n=6 in each group)