Table 2.

Patient stratification by the presence or absence of weight loss

Characteristic	All (n = 71)	> 5% weight loss in 1st year (n = 21)	No weight loss in 1st year (n = 50)	P-Value
Age (years)	71.3 ± 9.5	69.9 ± 8.7	71.9 ± 9.8	0.34
Female Gender	21 (29%)	7 (33%)	14 (28%)	0.78
Weight at diagnosis (kg)	88.6 ± 17.9	89.3 ± 14.1	88.3 ± 19.4	0.83
BMI at diagnosis	29.8 ± 4.94	30.6 ± 4.11	29.5 ± 5.23	0.40
Smoking (any)	50 (70%)	15 (71%)	35 (70%)	0.90
Pulmonary rehab	14 (18%)	5 (24%)	9 (16%)	0.52
Antidepressant	24 (33%)	5 (23%)	16 (32%)	0.38
Antifibrotic (any)	36 (51%)	13 (62%)	23 (46%)	0.30
Nintedanib	19 (27%)	7 (33%)	12 (24%)	0.56
Pirfenidone	17 (23%)	6 (29%)	11 (22%)	0.55
FVC at diagnosis (L)	2.9 ± 0.8	2.6 ± 0.8	3.1 ± 0.8	0.02*
FVC% Predicted	79.2 ± 19.4	70.5 ± 19.9	82.4 ± 18.3	0.02*
DLCO at diagnosis (mL/min/mm Hg)	11.6 ± 4.7	10.0 ± 4.5	12.3 ± 4.6	0.08
Reflux disease	31 (44%)	11 (52%)	20 (40%)	0.43
Diabetes	13 (18%)	5 (24%)	8 (16%)	0.50
OSA	9 (13%)	2 (10%)	7 (14%)	0.72
Oxygen use	22 (31%)	12 (57%)	10 (20%)	0.72

BMI: body mass index; DLCO: diffusion limitation for carbon monoxide; FVC: forced vital capacity; OSA: obstructive sleep apnea. *p < 0.05