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. 2022 Dec 21;14:1783–1801. doi: 10.2147/IJWH.S297062

Table 2.

SSRI/SNRI Luteal Phase or Symptom-Onset Dosing Showing Efficacy for Treatment of PMDD

Medication Dose Range Dosing Schedule
Sertraline 50 mg to 100 mg daily30,31 Luteal phase
50 mg to 100 mg daily49 Symptom-onset
Escitalopram 10 mg to 20 mg daily32 Luteal phase
10 mg to 20 mg daily33 Symptom-onset
Paroxetine 10 mg to 20 mg daily36,37 Luteal phase
12.5 mg to 25 mg daily (controlled release)38–40
Fluoxetine 10 mg to 20 mg daily41 Luteal phase
Venlafaxine 75 mg to 112.5 mg daily51 Luteal phase