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. 2022 Dec 21;9:1341–1352. doi: 10.2147/JHC.S388077

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© 2022 Duan et al.

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The combination of As₂O₃ and siNrf2 induced G1 cell cycle arrest of 5-FU-resistant HCC cells. The cell cycle was analyzed using flow cytometry after treatment with or without 20 μM As₂O₃ for 24 h in (A–D) SNU-387/5-FU and (E–H) Hep3B/5-FU cells. All data are expressed as mean ± SEM. *P < 0.05; **P < 0.01; versus the control group. ^#P < 0.05; versus the indicated groups.