TABLE 2.
Effect of CoQ10 on blood pressure, pulse volume, and total antioxidant capacity
| Baseline/end wash‐out | End of treatment | |||
|---|---|---|---|---|
| Placebo ➔ CoQ10 phytosome | CoQ10 phytosome ➔ placebo | Placebo ➔ CoQ10 phytosome | CoQ10 phytosome ➔ placebo | |
| SBP (mmHg) | 122.8 ± 4.1 | 122.0 ± 5.5 | 121.5 ± 3.3 | 123.1 ± 2.4 |
| DBP(mmHg) | 82.8 ± 1.9 | 82.3 ± 1.6 | 83.9 ± 1.7 | 83.2 ± 1.4 |
| PP (mmHg) | 39.5 ± 1.6 | 39.4 ± 1.8 | 37.9 ± 1.1 | 40.2 ± 1.6 |
| MAP (mmHg) | 96.4 ± 3.7 | 96.2 ± 3.6 | 96.5 ± 3.6 | 94.3 ± 3.0*,** |
| Endothelial reactivity (%) | 64.7 ± 5.6 | 64.1 ± 5.4 | 64.8 ± 5.8 | 68.5 ± 6.2* |
| TAC (pg/ml) | 10.1 ± 1.3. | 10.3 ± 1.4 | 10.4 ± 1.5 | 13.2 ± 1.4*,** |
Note: *p < 0.05 versus baseline; **p < 0.05 versus placebo.
Abbreviations: CoQ10, coenzyme Q10; DBP, diastolic blood pressure; MAP, mean arterial pressure; PP, pulse pressure; SBP, systolic blood pressure; TAC, total antioxidant capacity.