Table 5.
Ref | First author | Main findings |
---|---|---|
[20] | Zhu | Tumour size >40 mm, capsular invasion, metastatic cervical lymph nodes positively correlated with the risk of postoperative recurrence of MTC. |
[28] | Guo | In presence of cystic change, circumscribed margin, regular shape, no calcification, no rich vascularity, and normal cervical lymph nodes, MTC is easily misdiagnosed as benign by US. |
[30] | Wang | The higher frequency US presentation of MTC was the low‐echo tumour in round or quasi‐circular shape, with obscure boundary and often combined with rough calcification. |
[33] | Bao | The common US findings for MTC were solid composition, hypoechogenicity, regular sharp, well‐defined margin, and calcifications. |
[34] | Zhou | Sonographic features of MTC are similar to those of small papillary carcinomas but greatly different from those of large papillary ones. |
[36] | Sesti | US can detect recurrent MTCs with an accuracy positively correlated with calcitonin levels. |
[37] | Choi | The predominant US findings of MTC included solid internal content, round‐to‐oval shape, smooth margins, hypoechogenicity, and micro‐ or macro‐calcifications. |
[38] | Lee | MTCs differ from PTCs in size, presence of a cystic change, and echotexture. |
[39] | Cai | The typical sonographic features of MTC are hypoechogenicity, predominantly solid, irregularly shaped with intranodular micro‐ or macro‐calcifications. |
[40] | Kim | US findings for MTC are not greatly different from PTC except for the prevalence of an ovoid‐to‐round shape. |
[43] | Saller | Conventional US reveals a combination of hypoechogenicity, intranodular calcifications, and absence of ‘halo sign’ in the vast majority of MTC. |
Abbreviations: MTC, medullary thyroid carcinoma; PTC, papillary thyroid carcinoma; US, ultrasound.