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. 2022 Dec 12;10:1087363. doi: 10.3389/fbioe.2022.1087363

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Copyright © 2022 Liu, Huang, Mao, Jiang, Zheng, Wu, Cai, Liu and Dai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anti-wrinkle effect of Skin Pcluster in humans. (A,B) Before and after the treatment with eye cream (including 10% Skin Pcluster), VISIA was used to visualize the wrinkles around the eyes of the recruited volunteers. The number of wrinkles was quantified. (C) The representative photographs of healthy subjects’ neck and hand before and after treatment with essence containing 10% Skin Pcluster. (D) Images of facial wrinkles treated with a cream containing 10% Skin Pcluster. (E,F) Images of wrinkles around the eyes and on the forehead of the recruited volunteers were obtained by VISIA before and after treatment with eye cream containing 10% Skin Pcluster. p values were obtained by t-test.